What studies show about how many overdose deaths supervised drug consumption sites prevent each year. (Answer: Hardly any.)

The principal argument offered for creating supervised drug consumption sites is that they “are proven to save lives”--but seldom or never do supporters mention any specific numbers. Likely this is because the studies advocates claim prove their point actually show results most people would find deeply discouraging:

Research has consistently found that drug consumption sites aren’t effective in reducing what scientists term population-level overdose deaths (e.g., death rates at the state or national levels). This is primarily because the amount of drug use happening in society is multiple orders of magnitude larger than can be accommodated and rendered relatively “safer” within the sites, nor can the size or numbers of SCSs ever be scaled up enough to ever come close to bridging this difference.

  • Consider this: All of the 40 or so SCSs that exist nationwide in Canada put together host—i.e., divert from the street and make relatively “safer”—a combined total of 2,700 drug uses a day, with the average Canadian SCS hosting 45 uses daily, all according to official Canadian government data. A person addicted to fentanyl typically uses around eight times a day. So this means the average SCS makes “safer” the equivalent of just six users’ worth of drug use (45/8 = 5.6). Similarly, all the sites everywhere Canada combined divert about only three or four hundred fentanyl users’ worth of drug use (2,700/eight drug uses per day per person = 338). Given Canada has hundreds of thousands of drug users, and the United States has millions, it’s a mathematical impossibility for drug consumption sites to make a meaningful impact.

Nor are drug consumption sites effective in saving lives even when judging their effect at the most local level and their immediate community.

Research seeking to quantify the local impact on overdose deaths when a community opens an SCS has most commonly examined the “Insite” SCS in Vancouver that is the biggest SCS in the world by volume of use, hosting 2.9 million drug use visits since opening in 2003 (an average of 401/day). One well-known such study—cited again and again by Massachusetts SCS supporters as proof of concept—found that Insite likely averted between two and 12 overdose deaths a year. Another study, done for the Canadian government, found Insite likely averts one death a year. A study of a large SCS in Australia called Sydney United concluded that site probably averts about four deaths a year. Another study found a hypothetical SCS in Philadelphia having a capacity twice as big as Insite could save five lives a year. (See below for details and citations for all studies and figures mentioned here.)

In sum: studies suggest an SCS that operates at or above the scale of the biggest existing site in the world, Insite, may perhaps avert a handful of fatal overdose deaths a year. While every life matters, this result needs to be judged in proportion to the numbers of lives being lost: Boston has about 350 overdose deaths annually, Vancouver has over 600 and Philadelphia has around 1,400. Additionally, Insite is enormous, hosting nine times more volume of drug use than the average SCS in Canada (401/45 = 8.9). Extrapolating out Insite-like results to the performance of normal sites that are smaller suggests the typical SCS may not avert even one single overdose death in a given year.

Study: “Estimated Drug Overdose Deaths Averted by North America’s First Medically-Supervised Safer Injection Facility.”

Key finding: The Insite SCS (Vancouver, Canada) likely averted between 2 and 12 deaths a year, based upon comparison to the prevalence of overdose deaths occurring for use happening outside Insite in the same Downtown Eastside neighborhood during the 2004 to 2008 period covered by the study. Per the study: “Using these model inputs, the number of averted deaths were, respectively: 50.9 (95% CI: 23.6–78.1); 12.6 (95% CI: 9.6–15.7); 8.4 (95% CI: 6.5–10.4) during the study period, equal to 1.9 to 11.7 averted deaths per annum.”

What this would mean for Boston: A Supervised Drug Consumption Site that had the same impact as Insite did according to this study would reduce drug overdose deaths by between 0.5% and 3.5%. (Boston had 352 overdose fatalities in 2022)

Comment: This study and a related one by the same researcher group (described immediately below) have been repeatedly highlighted by SCS advocates in Massachusetts and nationally as their primary evidence for the contention that SCSs save lives, including specifically by: the “Massachusetts for Overdose Prevention Centers” coalition’s website (in its “Resources” section); SIFMA Now! website (in its “Explore the Research” page); MA Department of Public Health OPC Feasibility Report; a pro-SCS Boston Globe editorial; the Massachusetts Medical Society’s Report of the Task Force on Opioid Therapy and Physician Communication; and the

Citation: Milloy MJS, Kerr T, Tyndall M, Montaner J, Wood E (2008) Estimated Drug Overdose Deaths Averted by North America’s First Medically-Supervised Safer Injection Facility. PLoS ONE 3(10): e3351. doi:10.1371/journal.pone.0003351

Study: “Reduction in overdose mortality after the opening of North America's first medically supervised safer injecting facility: a retrospective population-based study” LINK

Key finding: Fatal overdoses within 500 meters [approx. 1/4 mile] of the Insite SCS location declined 35% during a two-plus year period examined after the Insite SCS opened in 2003, versus a 9.3% decline occurring in the rest of the city during the same period. There were 33 fatal overdoses in the 500 meter zone from 21 Sept 2003 to 31 Dec. 2005 (post SCS) versus 56 during the equivalent length of time occurring just prior to the SCS’s Sept. 2003 opening. [Expressed on an annualized basis, this would be 10.2 fewer deaths a year in the area around the SCS after it opened than before.]

What this would mean for Boston: A Boston SCS that had the same impact as Insite potentially did according to this study would reduce drug overdose deaths in Boston by 2.8%. (Boston had 352 overdose fatalities in 2022)

Citation: Marshall BD, Milloy MJ, Wood E, Montaner JS, Kerr T. Reduction in overdose mortality after the opening of North America's first medically supervised safer injecting facility: a retrospective population-based study. Lancet. 2011;377(9775):1429-1437

Study: “Predicting the impact of placing an overdose prevention site in Philadelphia: a mathematical modeling approach.” LINK

Key finding: A hypothetical SCS in Philadelphia equipped to accommodate 30 users at a time [ed. this would be more than twice as big as the world’s actual largest site, Insite] and operating 20 hours per day, seven days a week, was projected to avert six overdose deaths per year. Per the study: “Overdoses that occur onsite can be reversed. Our results predict that for every 30 stations in the overdose prevention site, 6 per year of these would have resulted in fatalities if they had occurred outside of the overdose prevention site.”

Citation: Wares, J.R., Dong, J., Gevertz, J.L. et al. Predicting the impact of placing an overdose prevention site in Philadelphia: a mathematical modeling approach. Harm Reduct J 18, 110 (2021). https://doi.org/10.1186/s12954-021-00559-4

Study: “Evaluating the population-level effects of overdose prevention sites and supervised consumption sites in British Columbia, Canada.” LINK

Key finding: A comprehensive analysis of all overdose events occurring in British Columbia, Canada during a three year period, 2015 through 2017, in which 25 Supervised Consumption Sites/Overdose Prevention Sites were opened in that province, “found no evidence that they reduce local hospitalization or mortality rates.” Per the study: “We found no statistically significant changes in opioid-related overdose mortality and hospitalization rates’ levels or trends following OPS/SCS implementation across matched L[ocal] H[ealth] A[rea] pairs.” The study was believed to constitute “the largest evaluation of the population-level effects of OPS/SCSs across a variety of settings, available to date.”

Citation: Panagiotoglou D (2022) Evaluating the population-level effects of overdose prevention sites and supervised consumption sites in British Columbia, Canada: Controlled interrupted time series. PLoS ONE 17(3): e0265665. https://doi.org/10.1371/journal.pone.0265665

Study: “A Cost – Benefit and Cost – Effectiveness Analysis of Vancouver’s Safe Injection Facility”

Key finding: The Insite SCS likely prevents one overdose death a year, based upon comparison to the prevalence of overdose deaths occurring for use happening outside Insite in the same Downtown Eastside neighborhood during the years examined by the study. Per the study: “Therefore, of the 50 potential deaths from overdose that are expected to occur in Insite each year, it would be expected that 1.08 actual deaths from overdose would actually occur if Insite did not have its current record of no overdose deaths. Consequently, through the prevention of death from overdose, Insite has prevented a further 1.08 deaths.”

What this would mean for Boston: A Boston SCS that had the same impact as Insite likely did according to this study would reduce drug overdose deaths in Boston by 0.3%. (Boston had 352 overdose fatalities in 2022)

Citation: Andresen, M and Boyd, N, A Cost – Benefit and Cost – Effectiveness Analysis of Vancouver’s Safe Injection Facility, January 2008

LINK

Study: “Supervised Injection Facilities and Other Supervised Consumption Sites: Effectiveness and Value; Evidence Report” LINK

Key finding: A hypothetical SCS in Boston is projected to prevent three overdose deaths a year, based upon assumptions about how large the envisioned site’s capacity would be and how much use it would get and the incidence of overdose fatalities in non-SCS settings. Per the study, such an SCS “was found to result in the prevention of three overdose deaths a year.”

What this would mean for Boston: A Boston SCS that had the same impact as projected by this study would reduce drug overdose deaths in Boston by 0.9%. (Boston had 352 overdose fatalities in 2022)

Citation: Armbrecht E, Guzauskas G, Hansen R, Pandey R, Fazioli K, Chapman R, Pearson SD, Rind DM. Supervised Injection Facilities and Other Supervised Consumption Sites: Effectiveness and Value; Evidence Report. Institute for Clinical and Economic Review, November 13, 2020

Study: “Final report on the evaluation of the Sydney Medically Supervised Injecting Centre” LINK

Key finding: The Uniting Sydney (Australia) SCS likely prevented about four overdose deaths per year. Per the study: “While there is no evidence that overdose deaths were prevented in the community, the MSIC did manage a large number of heroin overdoses and based on available epidemiological evidence and clinical information, it is likely that the MSIC prevented between four and nine deaths per year of operation, the lower estimate being the more conservative and plausible.”

What this would mean for Boston: A Boston SCS that had the same impact as the Sydney SCS likely did according to this study would reduce drug overdose deaths in Boston by 1.1%. (Boston had 352 overdose fatalities in 2022)

Citation: MSIC Evaluation Committee. (2003). Final report on the evaluation of the Sydney Medically Supervised Injecting Centre. Sydney: authors.